All participants provided written informed consent. Women who eat a Mediterranean diet supplemented with extra-virgin olive oil and mixed nuts may have a reduced risk of breast cancer. The Mediterranean diet incorporates the basics of healthy eating — plus a splash of flavorful olive oil and perhaps a glass of red wine — among other components characterizing the traditional cooking style of countries bordering the Mediterranean Sea. We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. Mayo Clinic Health Letter Medical Products Population Health and Wellness Programs Health Plan Administration Medical Laboratory Services Continuing Education for Medical Professionals Giving to Mayo Clinic Give Now Your Impact Frequently Asked Questions Contact Us to Give Give to Mayo Clinic Help set a new world standard in care for people everywhere. Request an Appointment Find a Doctor Find a Job Give Now. In fact, a meta-analysis of more than 1. Mediterranean diet: A heart-healthy eating plan The heart-healthy Mediterranean diet is a healthy eating plan based on typical foods and recipes of Mediterranean-style cooking. The two Mediterranean-diet groups had good adherence to the intervention, according to self-reported intake and biomarker analyses. Research has shown that the traditional Mediterranean diet reduces the risk of heart disease. Details of the trial design are provided elsewhere. Full Text of Methods. None of the sponsors had any role in the trial design, data analysis, or reporting of the results. 5 million healthy adults demonstrated that following a Mediterranean diet was associated with a reduced risk of cardiovascular mortality as well as overall mortality.
Most healthy diets include fruits, vegetables, fish and whole grains, and limit unhealthy fats. On the basis of the results of an interim analysis, the trial was stopped after a median follow-up of 4. While these parts of a healthy diet are tried-and-true, subtle variations or differences in proportions of certain foods may make a difference in your risk of heart disease. Abstract Background Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. Methods In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat). Give now. 10-12 The trial was designed and conducted by the authors, and the protocol was approved by the institutional review boards at all study locations. A primary end-point event occurred in 288 participants. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Participants received quarterly individual and group educational sessions and, depending on group assignment, free provision of extra-virgin olive oil, mixed nuts, or small nonfood gifts. Beginning on October 1, 2003, participants were randomly assigned, in a 1:1:1 ratio, to one of three dietary intervention groups: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with nuts, or a control diet. For these reasons, most if not all major scientific organizations encourage healthy adults to adapt a style of eating like that of the Mediterranean diet for prevention of major chronic diseases. 8 years. org. The primary end point was the rate of major cardiovascular events (myocardial infarction, stroke, or death from cardiovascular causes). Detailed enrollment criteria are provided in the Supplementary Appendix, available at NEJM.
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